Craving something tasty yet different? Try my Garlic Butter Shrimp Scampi Lasagna! This dish combines the rich flavors of shrimp scampi with classic lasagna. It’s easy to make and perfect for any occasion. Whether you’re a busy mom, an aspiring chef, or just looking to impress, you’ll love this flavorful twist. Let’s dive into the ingredients and cooking steps that will make your kitchen sizzle!
Why I Love This Recipe
- Unique Combination: This recipe creatively combines classic lasagna with the bold flavors of shrimp scampi, making it a standout dish.
- Rich and Creamy: The heavy cream and butter create a luscious sauce that perfectly envelops the layers of pasta and shrimp.
- Quick to Prepare: With a prep time of just 20 minutes, this lasagna is perfect for both weeknight dinners and special occasions.
- Customizable: You can easily swap out ingredients like spinach for other veggies or adjust the cheese to suit your taste.
Ingredients
List of Ingredients
- 12 lasagna noodles
- 1 pound large shrimp, peeled and deveined
- 4 tablespoons unsalted butter
- 4 cloves garlic, minced
- 1/2 teaspoon red pepper flakes
- 1 cup heavy cream
- 1 cup grated Parmesan cheese
- 1 cup shredded mozzarella cheese
- 2 cups fresh spinach, roughly chopped
- 1 tablespoon lemon juice
- Salt and pepper to taste
- Fresh parsley, chopped (for garnish)
Explanation of Key Ingredients
Each ingredient plays a special role in making this dish perfect.
- Lasagna noodles: These form the layers of the dish. Choose regular or no-boil noodles based on your preference.
- Shrimp: Large shrimp give a nice bite and flavor. They cook quickly, adding protein to the dish.
- Butter: Unsalted butter adds richness. It is key for sautéing and making the cream sauce.
- Garlic: Fresh garlic provides a strong, savory flavor. It pairs well with seafood.
- Red pepper flakes: These add a little heat, balancing the rich flavors.
- Heavy cream: This makes the sauce creamy and smooth. It binds everything together.
- Parmesan cheese: This cheese adds depth and a savory bite. It melts beautifully in the sauce.
- Mozzarella cheese: This cheese tops the dish, giving it a gooey, cheesy finish.
- Fresh spinach: Spinach adds color and nutrition. It wilts down, blending well.
- Lemon juice: This brightens the flavors and adds a fresh twist.
Substitutes for Allergens or Preferences
If you have allergies or preferences, here are some great swaps:
- Shrimp: Use chicken or firm tofu for a different protein.
- Butter: Replace with olive oil or vegan butter for a dairy-free option.
- Heavy cream: Use coconut cream for a dairy-free alternative.
- Parmesan cheese: Nutritional yeast can give a cheesy flavor without dairy.
- Mozzarella cheese: Try a plant-based mozzarella to keep it dairy-free.
- Spinach: Kale or Swiss chard can also work well in this dish.

Step-by-Step Instructions
Cooking Lasagna Noodles
Start by boiling a large pot of salted water. Once it boils, add the lasagna noodles. Cook them according to the package until they are al dente, usually about 8-10 minutes. Drain the noodles and set them aside. Be careful not to overcook them, or the lasagna will be mushy.
Sautéing the Shrimp
In a large skillet over medium heat, melt 2 tablespoons of butter. Add the minced garlic and stir for about 1 minute. The aroma will fill your kitchen, and it will smell amazing! Next, add the shrimp and red pepper flakes. Cook until the shrimp turn pink and opaque, which takes about 3-4 minutes. Once done, remove the shrimp from the skillet and set them aside.
Making the Cream Sauce
Using the same skillet, add the remaining butter and pour in the heavy cream. Stir the mixture and let it cook on low heat for about 3-4 minutes. You want it to thicken a bit. After that, add the lemon juice, salt, and pepper. Remove the skillet from the heat, then mix in the grated Parmesan cheese until it melts smoothly into the sauce.
Assembling the Lasagna
Grab a 9×13 inch baking dish. Start by spreading a layer of the cream sauce on the bottom. Place three lasagna noodles on top of the sauce. Next, layer half of the shrimp and half of the chopped spinach. Add another layer of cream sauce. Repeat this with another three noodles, the remaining shrimp, and spinach. Finish with the last three noodles and top with the rest of the cream sauce. Don’t forget to sprinkle the shredded mozzarella cheese on top.
Baking Instructions
Preheat your oven to 375°F (190°C). Cover the lasagna with aluminum foil and bake for 25 minutes. After that, remove the foil and bake for an extra 15 minutes. The top should be bubbly and golden brown. Let it sit for about 10 minutes before slicing. This helps the layers set nicely, making it easier to serve.
Tips & Tricks
Tips for Perfectly Cooked Shrimp
To get the best shrimp, use large, fresh shrimp. Make sure they are peeled and deveined. When cooking, heat your skillet to medium. Add butter and garlic first. Cook the garlic for one minute, then add the shrimp. Cook until they turn pink, about 3 to 4 minutes. Avoid overcooking, as shrimp can become tough. Remove shrimp from heat right away.
Best Ways to Layer Lasagna
Layering is key to a great lasagna. Start with a thin layer of cream sauce on the bottom. Place three lasagna noodles next. Add half of the shrimp and half of the spinach. Spread another layer of sauce over that. Repeat this process. Finish with three noodles and the last of the sauce. Top it off with mozzarella cheese. This helps create a creamy and tasty dish.
Serving Suggestions and Pairings
When serving your lasagna, let it sit for 10 minutes. This helps it hold its shape. Garnish with fresh parsley for a pop of color. Serve with a light salad for balance. A crisp green salad pairs well, adding freshness. For drinks, a chilled white wine works great. Enjoy your meal with friends or family for a fun evening!
Pro Tips
- Perfectly Cooked Shrimp: Make sure not to overcook the shrimp. They should be pink and opaque, which takes about 3-4 minutes. Overcooking can lead to rubbery shrimp.
- Layering for Flavor: To enhance the flavor, add a sprinkle of Parmesan cheese between each layer of noodles. This will create a more flavorful lasagna.
- Make Ahead: You can assemble the lasagna a day in advance and keep it in the refrigerator. Just add a few extra minutes to the baking time if baking straight from the fridge.
- Garnish for Freshness: Fresh parsley not only adds a pop of color but also brings a fresh flavor to the dish. Don’t skip this step for a beautiful presentation.

Variations
Adding Vegetables
You can boost flavor and nutrition by adding vegetables. Spinach works great, but you can choose others. Try mushrooms, zucchini, or bell peppers. Slice them thin. Sauté with garlic before adding to the lasagna. This adds color and taste. You can use any veggies you like. Just make sure they are cooked before layering.
Alternative Proteins
If shrimp is not your favorite, you have options. Chicken or scallops are great substitutes. You can also use firm tofu for a vegetarian twist. Cook them the same way as the shrimp. Season well with garlic and spices. This keeps the dish flavorful and fun. Feel free to mix different proteins too.
Dairy-Free or Vegan Options
Making this dish dairy-free or vegan is easy. Use plant-based butter and cream. You can find many brands that work well. For cheese, look for dairy-free options. Nutritional yeast adds a cheesy flavor, too. Also, make sure your shrimp or protein is plant-based. This way, everyone can enjoy the meal.
Storage Info
How to Store Leftovers
To keep your Garlic Butter Shrimp Scampi Lasagna fresh, let it cool first. Then, place it in an airtight container. Make sure to store it in the fridge. It should stay good for about 3 to 4 days. If you want to divide the lasagna, you can cut it into portions. This makes it easy to grab a quick meal later.
Reheating Instructions
When you’re ready to eat leftovers, reheat them properly. You can use the oven or microwave. For the oven, preheat it to 350°F (175°C). Cover the lasagna with foil to keep it moist. Heat for about 20-25 minutes or until warm. If you use the microwave, place a portion in a microwave-safe dish. Heat it in short bursts, about 1-2 minutes, checking in between.
Freezing Tips
Freezing is a great option if you want to save some lasagna for later. First, let it cool completely. Then, wrap it tightly in plastic wrap and foil or place it in a freezer-safe container. It will stay good for about 2-3 months in the freezer. When you’re ready to eat, thaw it overnight in the fridge before reheating.
FAQs
Can I make Garlic Butter Shrimp Scampi Lasagna ahead of time?
Yes, you can prepare this lasagna ahead of time. Just assemble it but do not bake it. Cover the dish tightly with plastic wrap or foil. You can store it in the fridge for up to 24 hours. When you’re ready to bake, take it out and allow it to sit at room temperature for about 30 minutes. Then, bake as directed.
What can I serve with this dish?
Garlic Butter Shrimp Scampi Lasagna pairs well with a fresh salad or garlic bread. A simple arugula salad with lemon vinaigrette adds a nice crunch. You can also serve it with a side of steamed veggies or roasted asparagus for a balanced meal.
How long does it take to bake?
Baking this lasagna takes about 40 minutes. First, cover it with foil and bake at 375°F (190°C) for 25 minutes. Then, remove the foil and bake for an additional 15 minutes to get a nice golden top.
Can I use frozen shrimp?
Yes, you can use frozen shrimp. Just make sure to thaw them first before cooking. Place them in the fridge overnight or run them under cold water for quick thawing. Once thawed, peel and devein them if needed. Then, follow the recipe as usual.
What is the best way to prevent lasagna from being watery?
To keep your lasagna from being watery, use a thick cream sauce and drain any excess liquid from the shrimp. You can also add less spinach or sauté it first to reduce moisture. Finally, let the lasagna sit for a few minutes after baking. This helps the layers set and makes for cleaner slices.
This blog covers how to make a delicious Garlic Butter Shrimp Scampi Lasagna. We’ve explored ingredients and shared key details about each. You learned about substitutes for allergies and preferences. The step-by-step guide takes you through cooking, sautéing shrimp, making sauce, and assembling everything.
With tips for perfect shrimp and layering, you’ll impress your guests. Don’t forget the variations for added flair! Lastly, proper storage tips ensure you enjoy every bite later. Now, you can create a tasty lasagna that shines at any meal. Enjoy your cooking adventur

Garlic Butter Shrimp Scampi Lasagna
Ingredients
- 12 noodles lasagna noodles
- 1 pound large shrimp, peeled and deveined
- 4 tablespoons unsalted butter
- 4 cloves garlic, minced
- 0.5 teaspoon red pepper flakes
- 1 cup heavy cream
- 1 cup grated Parmesan cheese
- 1 cup shredded mozzarella cheese
- 2 cups fresh spinach, roughly chopped
- 1 tablespoon lemon juice
- to taste salt and pepper
- for garnish fresh parsley, chopped
Instructions
- Cook Lasagna Noodles: Bring a large pot of salted water to a boil. Cook the lasagna noodles according to package instructions until al dente. Drain and set aside.
- Sauté Shrimp: In a large skillet over medium heat, melt 2 tablespoons of butter. Add the minced garlic and cook for about 1 minute until fragrant. Add the shrimp and red pepper flakes, cooking until the shrimp turn pink and opaque, about 3-4 minutes. Remove from skillet and set aside.
- Prepare Cream Sauce: In the same skillet, add the remaining butter and heavy cream. Stir to combine and cook on low heat for about 3-4 minutes until thickened. Incorporate the lemon juice, salt, and pepper. Remove from heat and stir in the Parmesan cheese until melted.
- Assemble Lasagna: In a 9x13 inch baking dish, spread a layer of the cream sauce on the bottom. Place three lasagna noodles on top, followed by half of the shrimp, half of the chopped spinach, and another layer of cream sauce. Repeat with another three noodles, the remaining shrimp, the remaining spinach, and another layer of sauce. Top with the final three noodles and finish with the rest of the cream sauce. Sprinkle mozzarella cheese on top.
- Bake: Preheat the oven to 375°F (190°C). Cover the lasagna with aluminum foil and bake for 25 minutes. Remove foil and bake for an additional 15 minutes until the top is bubbly and golden brown.
- Garnish and Serve: Let the lasagna sit for 10 minutes before slicing. Garnish with fresh parsley before serving.


